I haven't seen the panel myself yet, but after witnessing the endings and reading your post, Henry, I'm fully assured in my decision to not pre-order the next game and wait at least 6 months after the release to read about the state of the game. I've never seen game developers say that they're simply tired of their own game, and it's not encouraging me to trust this won't happen again.
Hopefully the modders do their magic and give us a good amount of improvements we'd like to see.