I followed your tips and cleared most of the inventory. It was a bit frustrating though because I liked to collect books and some worthless itens just for the sake of it. However it was way more frustrating losing an entire afternoon of progress because the game freezes while spliting 2 Acid Vials into 1.
I wonder how one would play an Ironman mode run?
Sorry to hear that. I'm used to add worthless items to wares when looted, in order to sell them conveniently. I wonder if that's why I've got through the game three times on PS5, but never had this issue.
