Honestly I wish it was at least based off if you had him kill Karlach or not. That choice really makes no difference outside of the horns which is crazy. You'd think his personality would've changed a wee bit but nada.
It makes a change for the tiefling party. If you saved Karlach he is moping because he might be seen as a devil by the people who have just also been dragged into hell against their will. If you kill Karlach, he is starting to question if he can ever be the hero he wants to be while he has to do Mizora's bidding. But it would be cool, if this made a difference in his final choice.
If it's a consolation to you, fylimar, Mizora has at least been moved to the far side of the act 3 harbour camp now, so she is at least not standing directly next to Wyll any longer.