It's worth a try to go into C:\Users\-Your Windows Username-\AppData\Local\Larian Studios and deleting the modsettings.lsx inside the playerprofiles folder. Could be messing with the game, otherwise delete the entire BG3 folder if it still doesn't work.
You can get there by clicking on the Windows icon and typing %localappdata%. Be sure to take out any savefiles worth preserving before deleting the folder though.
