I had the same issue. The game was running fine on my old PC, but when I bought a new config, the game started to crash when I tried to load a saved game. If it loaded succesfully first, then it crashed on another load, while other (more demanding games) were running just fine.

I've tried everything, installed Windows 11, then installed WIndows 10 again, fiddled with the GPU overclocking, updating drivers, turning off Steam cloud saves, and everything else I read in forums, yet nothing seemed to help.

But when I set the game's exe (not the launcher) to start in administrator mode, the problem was solved. Or at least it is for now.

My config is:
- Operating System: Windows 10
- Processor: Intel Core i7 12700KF
- Memory: 32 GB RAM (2x16GB Kingston Fury 3200 MHz)
- Motherboard: ASRock H610M-HVS/M.2 R2.0
- Graphics Card: AMD Radeon RX 7800 XT 16GB (Sapphire)
- PSU: Keep Out FX800B 800W