I'm not sure when this manifested; I am currently running v4.1.1.5970269, but last time I was in the Emerald Grove, it must've been v4.1.1.4953010 or even earlier.

Anyway, Pandirna is lying on the floor, both Paralyzed and Knocked Down.
It is possible to "Help" her up, but all this does is make her spot you and trigger her first interaction.

Any further attempts to "Help" her up only immediately results in her being Knocked Down immediately again, making it impossible to initiate dialogue.

[Linked Image from i.ibb.co]

I have a lot of mods running, but none that even remotely touch upon Pandirna or the general application of Paralyze or Knocked Down, and in fact, I can't find any references online to Pandirna being "Knocked Down", nor to "Knocked Down" as a discrete condition (just various forms of Prone, which does not include Knocked Down).