The game is designed so you can do whatever you want. It is not like Pathfinder games that will kill you if you didn't optimise your build well enough. Pick whatever race and class seems most cool to you. You can also pretty freely respec later on if you want to change your class later.
Like others I would recommend Custom first - perhaps, Dark Urge, as from what I played I found his bits less effective, knowing the vanilla run.
