Wyll might be the only origin, I would maybe play at some point. He has main character energy, is pretty involved in the main plot and as RQ mentioned: his patron is actually in the game and the stakes are high.
I have different relationships with the companions depending on who I play.
I also choose romances mostly by the roleplaying aspect. If I would go by attraction, I would romance Karlach every time, but I romanced everyone with different characters ( apart from Halsin and Minthara, the latter just never liked me enough to start a romance in act 3, I'm too good for her, literally :-D)
