Running a D&D campaign is very different from creating custom levels for a video game. If I were to start using a modded BG3 as a virtual table top, I'd need to create or find full 3D environments for every encounter location at the very least - possibly all the main areas of cities and the roads between them, too. I couldn't just hand-wave travel except for any encounters on the way. And I'd need to script all the events and all the puzzles, rather than just narrating them. This is probably why WotC's attempt at a full 3D VTT recently failed. 3D interactive D&D seems cool, until you start thinking about what it actually requires from a GM