I had a lot of fun in Act 1 with a party of 5, and next time I want to play it with a party of 6. The "toilet chain" is annoying at times, of course, but you can also approach the encounters with two mini-squads a la Jagged Alliance 2.
The Dank Crypt Chapel is the best example of this. I ambushed Gimblebock and Friendos from two sides. But when I jumped through the cracked floor, the “House-to-house combat” becomes confining. But overall I just like having more options due to the larger party. I wish Larian would support a larger party or mods for it much better.
Let's see how “messy” it gets with RTwP when all mods are ready and the game remains stable: