Larian Studios Forums Baldur's Gate III Baldur's Gate III - Story & Character Discussion About the companions... (Full SPOILERS)

It's a lot less strange when you consider that the 3 antagonists are the chosen of gods.

Ketheric is the chosen of Myrkul.

Gortash is the chosen of Bane.

Orin is the chosen of Bhaal.

So, people who are contesting them or outright beating them are likely going to get the attention of gods.