Gith'yanki do not have quite the same psychology as the RL people around you. Lae'zel was brought up as a killing machine. She killed her cousins when she was still a girl. Still, she softens up quite a lot throughout the game. Her mind does not totally switch to human culture and customs, but she 's come a long way, IMO.
And Shart, well, what have they done to her. ! She was made to torture her own parents without knowing. Give her some time to adjust, right ? At Wither's reunion party, she wants a quiet life tending to animals and plants. If yoou've romanced her, she wants to do this with you. Looks like a good and eternal friendship.
Karlach is extremely likable, despite 10 years in hell, and her life hanging on a thread. A bit foulmouthed maybe, but her infernal iron heart is figuratively one made of gold. You cvan get a lot of friendship back from her.
Haven't romanced Wyll or Gale, but I think they will become good friends. Astarion, a vampire spawn, can hardly be measured to human standards also.
I find the track that the companions make very interesting. And I did find a strong bond of friendship with some. Karlach and Shadowheart especially.