When you say you have no mods, does this mean you never ever tried mods on this computer system yet?
Reason I ask is because if you used mods in the past and later removed them, they might still be spooking up with left overs until you do a proper full clean reinstall of the game.
I assume these honor mode runs were started with a clean install of the game with no modding behind them, with that being said I suspect you might want to be more persistent with the Larian Support staff, something might be getting corrupted when it always happens at the same specific spot of the game.
What did the support suggest?
Last edited by Xenonian; 3 hours ago.