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If you take the survivor curse (several clicks to get her really down - her spiritual resistance is pretty high), Josie should have a white spot on her body this symbol shows, she's cursed. Then simply hit the pause button, choose the polymorph spell in peace and quiet and polymorph her.
You don't have to touch her, it's a long distance spell, but you should target her, it's no area spell.


I cursed her with Curse (not Withering Curse) spell for about 20-25 times in a row. My Mana is 362, I used about 2,5 of whole amount of it (I drank 3 restorations when mana was about half). No particular spot on her body appeared. She was surrounded with a cloud of glimmering red and pink and a white center. If by "white spot" you meant a kind of white eye on the hips (which I get when SHE curses me) - she didn't have anything like that. Then I tried Polymorph, but she stayed in her own shape. It seems that something that I do I do wrong. Should I use Curse on her longer?