I have entered Maradino's study multiple times and have never found a book called "book" to open the stone door to get the blood shard.

I have reloaded the game from different save points and still have not found a book...

Not sure if doing a certain quest before going to the study can make this happen

Are you holding the ALT key while looking around? if you are and still can't see it there then your game is borked

Ya I think your right, no luck in the game with the book. Guess i'm starting over