Unfortunately, it seems that you (and I) are in the minority. I made a post about this same subject(
Obtrusive Info Panels). One person replied that he didn't see it as a problem. Although there were 58 reads, there were no confirming replies. Just the same, I agree with you, not only when trying to pick up items revealed with [Alt], but when sorting my inventory too. I want to move an item, but the place where I think I have a empty slot is hidden behind the info panel. I've played pretty much every CRPG over the last 20 years and I don't remember any that had such obtrusive tooltips/info panels.