I always start all RPGs on the hardest setting. Doing so with divine divinity turned out to be a big mistake, even if I had the latest patch english 1.0 (1.34) at the time, it resulted in:
I had to do things in a very diffrent order from what the creators had considered, I can give alot of examples even if it was quite some time ago if anyone is intressed. However this resulted in a huge amout of bugs, so many in fact that I got tired of the game, and didn't even finish it. The other problem was the game was not hard, the only thing the hard setting did was make some monsters hard to kill, and it gave a very unbalanced feeling, like the hard setting hadn't been much considered at all, I can give examples of this aswell.
Don't make the same mistake with Beyond Divinity, I know there's only a few people that start a game on hard, but eventually people will jump to it on a second time through.