She said in a different topic she only had the one drive.
Do you have access to a different computer you could try? That would at least help determine if the CD itself was the problem, rather than a conflict between the copy protection and the optical drive (though if that was the case, it shouldn't have worked the first time). Perhaps re-install the game? Maybe install the
patch after rebooting the computer on install, but before trying to run the game (or try the unpatched game first if that was what you did).