I played Dota2 and defiance with no issues. It seems like it happens mostly when the intensity picks up. When engaging units or lots of things going on seems to be the worst. While building units and just over viewing the map it doesn't seem that bad.
I lowered the graphics to as low as they could and the issue still persisted. It did seem like it might have eased up though.
I did make sure everything is up to date with windows and my drivers.
I also changed the nvidia control panel to maximum performance and ran as administrator.
Issue seemed to be less as frequent but it still happened.
This problem might not be because of the game.
-Please make sure that the videocard is in the slot firmly, loosened videocards can cause a driver failure when intensity is high.
-Don't use beta nvidia drivers, they're known to have stability issues.
-If a windows hadn't been reinstalled for a long time, the registry gets full of trash data, some of which can cause some drivers to fail at times.
If none of these, than there might be 3 explanations:
-It's the game's fault(this might be the cause if none of the above helped you, but i'd start saving money for a new videocard/psu just in case).
-Your videocard is dying.
-Not enough power from psu for videocard when under high load, and so the nvidia driver glitches out.