It can be downright funny.
You can kill Eglander for being a raving bloodthirsty loon who hires others to do his dirty work, and get an "innocent kill" convo.
Or you can kill Victoria after failing to steal her necklace, and... nothing.
I got tired of his constant rambling about torturer this and thousand needles that, and since I can't steal his amulet, I decided to whack him. After the fight, "innocent kill" convo comes up, I say that we should watch what we hit in the future, my second agrees, +Compassion. And then she immediately kicks off the follow-up convo and says that I became very compassionate in the course of our adventure!