This is a known issue, which is being investigated. There will at least be a fix for the Eternal Arbiter being hostile in the next game update; there is no ETA for that yet, though.
A handful of people have reported this issue, and some supplied saves, but unfortunately none had saves before arriving at the Nameless Isle, or before this problem started, and QA has been unable to reproduce this alignment issue (it wasn't evident from the saves what triggered the alignment change).
A couple of people have had Han turn hostile (being a child, he can not join combat), as well as Sergeant Zrilla (at least in one case quickly killed by Jahan), etc.
If you still have saves before this first started and are playing on PC, please email supportdos2@larian.com with your latest save (or email/post a Dropbox or Google drive link, etc), as well as the most recent save where Han (etc) is friendly and the oldest where he is not. If you are using any mods, also include a list of those enabled and/or the modsettings.lsx from your profile folder.
Each save is a folder in the '..\Documents\Larian Studios\Divinity Original Sin 2 Definitive Edition\PlayerProfiles\<ProfileName>\Savegames\Story' folder.
In Windows Explorer you can zip a file or folder by right clicking on it/them and selecting 'Send To | Compressed (zipped) Folder' (and similarly in OSX/Finder).
PS4 saves can be sent, as well, but they would need to be transferred to a USB flash drive first.
In the Saved Data in System Storage section of the Settings menu, click Copy to USB Storage Device, select the relevant save(s) and Copy. From there you can zip the files, then copy to email or upload somewhere and provide a link.