I'm not sure if this is entirely related to the issues which everyone else in this thread are dealing with, but recently whenever I load a save, the game starts taking up a massive amount of physical memory on my computer (98%, give or take). It started maybe three days ago, and wasn't an issue at all before that point. I'm currently a few hours into exploring Reaper's Coast (specifically right outside of some witches cottage), after escaping Fort Joy. I've got 8Gig of RAM- I would think that from playing everything until now, my computer should be able to handle the game fine.