My drive is going down (read speed dead slow) because of the hammering it gets. Like I've said before, if they want to check if a copy is original, they should do it on the installation, not during the launch of the game.
I have often wondered, what's the point in doing a full install if you still need the disc in? I nearly always download "No-CD" patches for games. I am at the point where I won't buy games that don't have these patches. They can degrade the games performace, and hammer my drives.
And besides, let's not pretend these protections stop people copying the games, piracy is as old as the industry itself. And let's not forget, it is also illegal to copy protect software over here in the UK. Bearing that in mind, it's a bit cheeky calling pirates for breaking the law, isn't it.