Ok so it looks like there aren't any unique items found until FOV?
Im stocking up on blessed melee damage charms, because they are far more valuable to an unarmed character where a +8 to melee is almost tripled in terms of extra damage with maxed out unarmed skill and strength. Especially on nightmare mode where it's hard to fight enemies close up without dying unless you can reduce the numbers quickly.
Theres 4 dealers that sell charms, so im visiting them each time I level up to stock up on them. Have already wasted quite a few on equipment when Ive then found much better.