To the posters above you, your crashes might be related to elemental ground effects crashing your games like mine (Fire seems fine but poison clouds will 100% crash the game whenever I load/teleport or even walk into that area.)
So I went to an area where I previously crashed and it crashed to desktop again, in the same area. This was west of the market in the area with the level 3/4 mobs on route to the lighthouse.
The area where I crashed has poison on the ground - I am not sure how important this is but it ties in with what has been said by Eldiora regarding elemental ground effects crashing the game. Also this is an area that I have cleared of the mobs.
EDIT: I deleted the file "cyseal.lsb" as described in
this thread which worked and allowed me to move freely passed the areas in the game where I would have crashed before. The only downside to this is the mobs have reappeared and the areas in my map are hidden again.
