Quoting this from the game's manual:

"Hovering over the target will also show your chance of a successful hit
on that enemy. Your chance depends on the primary statistic related to
your specific type of attack and weapon,your offence rating , as well as
the enemy's defence rating. Enemies with lower defence ratings tend to
be easy to attack, while those with higher defence ratings can be very
difficult to hit.
"

Your chance to hit depends not only on your offence rating but also on the enemy's defence rating. So, if you see a very low chance to hit, then the enemy has a very high defence rating - one of the possible reasons is that you are fighting enemies who are above your level. When I picked up fights with my level 11 characters against level 14 spiders, then the chance to hit of my warrior was even worse than 49% - it was actually just 29%. Btw, my warrior had strength of 13 at this time.

Last edited by Elwyn; 05/08/14 10:01 PM.