Personally, I prefer turn based for hard fights and RTwP for trash mobs. It's nice on easy fights to just let the AI quickly dispatch the mobs. Trash fights are good, they make you feel like your character is strong, and it gets tedious when you have to pull out all the stops for every fight.
I thought Obsidian made an excellent call with POE2 with the option to play turn based. What would be great is if Larian evolved that idea a bit further by allowing the player to switch between RTwP and turn based at any time, sort of like VATS.
Give the players what they want, the best of both worlds!