I can't remember which game it is, but they use pop ups for reactions and it gets annoying pretty fast. Reaction-wise, I think both RTwP and TB will waste resources and neither will have much of a difference. However, one does not have to worry about accidentally shooting a fireball, or using a rage, and that's what I mean by RTwP having a disadvantage here. But yeah, reactions will be a pain. But sometimes I save a reaction for a specific enemy, so I let one thing slide but then the enemy I'm looking out for doesn't do what I expected so I let that thing slide for no reason. I doubt it will make much of a difference, but at least I won't have to deal with those cases anymore lol