I was able to load yesterday (once)after multiple attempts by using DX11. Was able to create a character and start the game. Tried loading today probably about 50 times and nothing that I tried worked - updated drivers etc and switched from DX11 to Vulcan . My Profile and savegame are in the system files so the game did work at some point. I'm on steam and there was a hotfix today - perhaps it "unfixed" my game. BTW I did report each crash to Larian