Shadowheart has a voice line where she says; "Usurping the gods' domains? I just want my brain back!" which to me is an indication of the fact that the "good" and "evil" paths in Act 1 are going to become irrelevant once we get to Moonrise and it is revealed the Absolute is trying to become the new Divine and replace Lucian usher in the age of mortals.
Of course, all of our feedback on the evil path is still valuable, but it is worth keeping this in mind should we eventually see it proven to be true.
I'm pretty sure none of what we do in act 1 would have any influence on act 2. In dos2 even killing Alexander (which is an unavoidable fight mind you) doesn't affect anything lol