You didn't ask where/how to get the mark of the Absolute, so don't read the next part if you don't want it spoiled...

If you want to get the mark, you need to talk to Priestess Gut in the Goblin Camp.

And the gloves aren't the only item you need the mark to use. There is also a shield dropped by Gut that you need the mark for.

I don't know yet if there are any serious drawbacks to getting the mark. We probably won't find that out until EA is done and the full game is released.