Having taken a really good look at Pathfinder: Wrath of the Righteous over the weekend, and just the sheer amount of depth in it – FAR more classes, subclasses, skills and abilities than anything in the 5E PHB - I don’t think Larian should have any issue translating D&D into a reasonably faithful rendition of 5E. Owlcat has a much smaller team too.
Its not a question of possibility. Its an issue of if they desire to do it. Pathfinder, and Solasta make it perfectly clear.