I’ve been pondering the significance of Jeremy Crawford joining Larian for the Panel from Hell this week. Since he’s the principal 5E rules designer at Wizards, why do you think he’s been invited for this panel? It could be they are wheeling him out to explain why 5E rules don’t need to be translated to a video game faithfully? Or perhaps they’re going the other way and leaning more into 5E so he’s there to explain how they’ve worked hard in 5E on the action economy and balance and Larian are moving to emulate that?
Had the same thought / worry. It will be an interesting test for WotC because if they take a "these are just house rules and Larian is the DM" line they will do some damage to their reputation.
I mean if house rules can deviate this much why pay WotC for a ruleset anyway?
At your table the rules can deviate as much as your group wishes.