At the toll house, once you engage in a dialog with Anders and you "end" the dialog, the game doesn't let you save. You get a warning saying you can't save in mid-dialog ...
Even after fighter Anders and his crew, and after going to camp for a rest, you can't save - for same reason. Reloading the previous save, before meeting Anders, will not help you. I had to reload the game with the "previous" save that I couldn't save before and then it saved.
I was not able to reproduce the bug