I really want the attack option in the first meeting with Astarion. I mean, the guy attacks you with a knife, depending on the character I play, that is a nogo.
And yes, Raphael too. I get, that he is important for the plot, but I don't ask to kill him, just show him, how displeased I am with his behavior.

"We are all stories in the end. Just make it a good one."

Doctor Who