Currently in scenario where you have to free Nere if you choose to
get the smoke powder from the hidden stash rather than bargain for the canaster (or do something else that causes Larida to blow herself up)
, The explosion sets the ground on fire, and if Thrinn randomly steps in it (which she has done multiple times on my recent play through) she takes damage and that causes combat to start immediately bypassing the interaction with Nere.

This is a problem for several reasons:

[Linked Image from i.imgur.com]