Especially inside buildings, and with multiple levels I'm consuming my ssd with F5-F8... You have to save before EVERY move because you seldom do what you intended to.
I'm not entirely sure what issue you're having in combat?
It's rare that I misclick anywhere, and with edge panning enabled, I can generally move the camera around with my mouse to get a good view of everything. And as the the poster above mentions, double clicking on your character recenters the camera.